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The effects of launching and landing has various effects on astronauts, with the most significant effects that occur being space motion sickness, orthostatic intolerance, and cardiovascular events.
Space motion sickness is an event that can occur within minutes of being in changing gravity environments (i.e. from 1g on Earth prior to launch to more than 1g during launch, and then from microgravity in space to hypergravity during re-entry and again to 1g after landing). The symptoms range from drowsiness and headaches, to nausea and vomiting. There are three general categories of space motion sickness:
Mild: One to several transient symptoms, no operational impact
Moderate: Several symptoms of persistent nature, minimal operational impact
Severe: Several symptoms of persistent nature, significant impact on performance
About three-fourths of astronauts experience space motion sickness, with effects rarely exceeding two days. There is a risk for post-flight motion sickness, however this is only significant following long-duration space missions.
Post-flight, following exposure to microgravity, the vestibular system, located in the inner ear is disrupted because of the microgravity-induced unresponsiveness of the otoliths which are small calcareous concretions that sense body postures and are responsible for ensuring proper balance. In most cases, this leads to some postflight postural illusions.
Cardiovascular events represent important factors during the three phases of a space mission. They can be divided in:
Pre-existing cardiovascular diseases: these are typically selected-out during astronaut selection, but if they are present in an astronaut they can worsen over the course of the spaceflight.
Cardiovascular events and changes occurring during spaceflight: these are due to body fluids shift and redistribution, heart rhythm disturbances and decrease in maximal exercise capacity in the micro gravity environment. These effects can potentially lead the crew to be severely incapacitated upon return to a gravitational environment and thus unable to egress a spacecraft without assistance.
Orthostatic intolerance leading to syncope during post-flight stand test.